You deserve to feel like yourself again.
If depression hasn't lifted despite trying everything, you're not out of options. SPRAVATO® is the only FDA-approved ketamine-based nasal spray for hard-to-treat depression — and our team is here to walk with you, every step.
You Are Not Alone
Hard-to-treat depression is more common than you might think — and it is not a sign of failure. When standard antidepressants haven't been enough, there is another way forward.
adults with depression don't get enough relief from standard antidepressants.
not weeks — many patients feel improvement remarkably quickly with SPRAVATO®.
the first and only FDA-approved esketamine nasal spray for treatment-resistant depression.
A Gentler Way Toward Relief
SPRAVATO® is a prescription nasal spray taken alongside an oral antidepressant. It works by increasing glutamate, a natural chemical that helps brain cells communicate — improving mood through a completely different pathway than traditional medications.
Because it works so quickly, relief can begin within hours. For many people who have waited months or years to feel better, that difference can be life-changing.
For the first time in years, I felt like the fog lifted. I finally feel like myself again — present for my family, hopeful about the future.
Your Path Forward
SPRAVATO® follows a supportive, phased plan. We'll be with you at each stage, adjusting care to how you respond.
Getting Started
Two gentle sessions per week to build therapeutic levels and begin easing symptoms.
Finding Your Rhythm
One session per week, with care tailored to your personal response and progress.
Staying Well
Every one to two weeks, gradually spacing out as you continue to feel better.
Cared For, Every Step
Every session takes place in a calm, private room at our certified REMS center, with a trained clinician monitoring you throughout. SPRAVATO® is not a narcotic and is not considered addictive when administered under medical supervision. You're never on your own.
Your Questions, Answered
It's normal to have questions. Here are the ones we hear most.